Ralph A. Nixon MD PhD

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Ralph A. Nixon, MD, PhD laboratory | Center for Dementia Research

Director, Center for Dementia Research. Director, Laboratories of Molecular Neuroscience. Ralph.Nixon@nki.rfmh.org. Professor, Departments of Psychiatry and Cell Biology. NYU Grossman School of Medicine. Nixon NYU Page. Ralph.Nixon@nyulangone.org. (845)398-5423. (845)398-5422.

Ralph A. Nixon, MD, PhD | Center for Dementia Research

(845)398-5423 (845)398-5422 The CDR aims to understand the molecular causes of Alzheimer's Disease and related dementia pathogenesis and to develop and validate innovative therapies for these disorders at their earliest stage.

Ralph A. Nixon, MD, PhD - NYU Langone Health

Summary. In major neurodegenerative diseases, such as Alzheimer's and Parkinson's, the abnormal accumulation of one or more polypeptides within or around neurons is central to pathogenesis. Our research focuses on two aspects of neurobiology that govern the fate of normal and pathogenic proteins: the regulation of proteolytic processing and the ...

Neuroscience Institute Faculty | NYU Langone Health

NYU Langone's Neuroscience Institute research faculty drive biomedical innovation through interdisciplinary research. Learn More ... Ralph A. Nixon, MD, PhD Professor, Department of Psychiatry ... Phone: 845-398-5423. Close. Dimitris G. Placantonakis, MD, PhD.

Ralph A. Nixon MD PhD - 140 Old Orangeburg Road, 3rd Ave Bldg35 ...

Ralph A. Nixon MD PhD is a Doctor located in 140 Old Orangeburg Road, 3rd Ave Bldg35, Orangeburg, New York, US . Phone number, Photo, Opening hour, Payment method and Map details of Ralph A. Nixon MD PhD inside. ... Write a Review; Share; Photos: Contact and Address. Phone: +1 845-398-5423. Address: 140 Old Orangeburg Road, 3rd Ave Bldg35 ...

Ralph Nixon's Instagram, Twitter & Facebook on IDCrawl

Ralph A. Nixon, MD, PhD | Center for Dementia Research Ralph.Nixon@nki.rfmh.org Professor of Psychiatry and Cell Biology NYU Langone Medical Center Nixon NYU Page Ralph.Nixon@nyulangone.org P: (845)398-5423 : F: (845)398-5422 Education A.B. Brandeis University, Waltham, MA Ph.D.(Cell …

β2-adrenergic agonists rescue lysosome acidification and function in ...

INTRODUCTION. Lysosomal dysfunction is implicated in the pathogenesis of an increasing number of neurodegenerative disorders, including Alzheimer's Disease (AD) and Parkinson's Disease (PD) [1-6].Common features of these disease states are delayed vesicular trafficking, reduced lysosomal proteolysis, and marked accumulation of autophagy substrates and protein aggregates [7-9].

Presenilin 1 maintains lysosomal Ca2+ homeostasis by regulating vATPase ...

Introduction. PS1 is primarily known to be a catalytic component of γ-secretase complex, which carries out cleavage of amyloid precursor protein yielding Abeta peptides, which in various forms have been implicated in AD pathogenesis (Chavez-Gutierrez et al., 2012; De Strooper and Annaert, 2010; Selkoe and Wolfe, 2007; Steiner and Haass, 2000).Loss of function mutations of PS1 that cause early ...